Gun crime is a major cause of fear and distress throughout the UK. The problem is deeply entrenched in a wide range of social and cultural factors and therefore not an isolated issue.

I'd die if I was Madonna. I'd die. God what a horrible way to live. And Michael Jackson! To be so famous and to feel so isolated. I feel so bad for them. I don't know how it feels and I hope it never happens to me.

I felt so painfully isolated that I vowed I would get revenge on the world by becoming a famous cartoonist.

My mother isolated herself from all family and friends for some 20 years. And never met her grandchild my son.

This attempt to isolate cell constituents might have been a failure if they had been destroyed by the relative brutality of the technique employed. But this did not happen.

Acting can be a narrow and isolated experience because you only examine your particular part.

A company that pays attention to the family unit is a successful company. We don't isolate the family. We don't make rides that say 'Hey mom dad you go sit on the bench.'

Unless there is meaningful change in Syria and an end to the crackdown President Assad and those around him will find themselves isolated internationally and discredited within Syria.

By its very nature the beautiful is isolated from everything else. From beauty no road leads to reality.

An aphorism ought to be entirely isolated from the surrounding world like a little work of art and complete in itself like a hedgehog.

It is after all the greatest art to limit and isolate oneself.

When I was working on Eye of the Beholder I played a character who is so aloof that my whole lifestyle became very aloof. If someone knocked on my door there was a part of me that went into a rage because I wanted to be isolated and alone.

I love working with a cast and a group of people every day which is different than recording because you're usually pretty isolated and alone. They serve as a good balance for each other.

I can work myself up into a fearful paralyzing state of mind that can last for days weeks even months where I feel mad totally isolated and alone overwhelmed and completely out of control.

Christmas lights may be the loneliest thing for me especially if you mix them up with reindeers and sleighs. I feel alone. I feel isolated. I feel I do not belong.

The Jew does not wish to be isolated. He fears being alone without allies.

The majority does not rule in America but the minority shouldn't hijack it. And it's because we're afraid. They have isolated us and made us feel as though we're alone. We're not.