Clinton is a big personality who has led a big life and for some of the media conventional wisdom to boil it down to a view that 'all people are really interested in' are a few moments of madness in the Oval Office gets him the importance of the presidency and the significance of his life all wrong.

In time it will become clear to everyone that support for the policies of pre-emptive war and interventionist nation-building will have much greater significance than the removal of Saddam Hussein itself.

Just as we could have rode into the sunset along came the Internet and it tripled the significance of the PC.

An organization which claims to be working for the needs of a community - as SNCC does - must work to provide that community with a position of strength from which to make its voice heard. This is the significance of black power beyond the slogan.

But actually so many of the clerics that I've met particularly the Church of England clerics are people of such extraordinary smugness and arrogance and conceitedness who are extraordinarily presumptuous about the significance of their position in society.

For me science is already fantastical enough. Unlocking the secrets of nature with fundamental physics or cosmology or astrobiology leads you into a wonderland compared with which beliefs in things like alien abductions pale into insignificance.

Almost the only persons who may be said to comprehend even approximately the significance principles and purposes of Socialism are the chief leaders of the extreme wings of the Socialistic forces and perhaps a few of the money kings themselves.

And of course identifying all human genes and proteins will have great medical significance.

When I talk about the importance of the institution of marriage I think of the commitment and the significance of standing in front of those closest to you and promising fidelity to your partner 'til death do you part.'

If we wish to know the force of human genius we should read Shakespeare. If we wish to see the insignificance of human learning we may study his commentators.

Humans may or may not have cosmic significance and if they do it will be by hitching a ride on the objective centrality of knowledge in the cosmic scheme of things.

A toothache or a violent passion is not necessarily diminished by our knowledge of its causes its character its importance or insignificance.

Even a purely moral act that has no hope of any immediate and visible political effect can gradually and indirectly over time gain in political significance.

I'm so intrigued by women throughout history where the significance of what they were representing at that time is obscured by the fact a man saved them or they were prostitutes.

History is the interpretation of the significance that the past has for us.

I've been quite fascinated by the relative insignificance of human existence the shortness of life. We might as well be a letter in a word in a sentence on a page in a book in a library in a city in one country in this enormous universe! And that kind of fear and insignificance has kept me awake at night.

We give a lot of others significance in our lives even when they don't deserve it. It doesn't matter if they're family or if you've known them forever. If they're not good for you they've got to go.